LOLINE ALKALOID EFFECTS ON GASTROINTESTINAL NEMATODES

Loline Alkaloid Effects on Gastrointestinal Nematodes

Loline, an alkaloid with several derivatives, has suggested antimicrobial and anthelmintic properties.Therefore, loline was investigated as a natural anthelmintic against Trichostrongylus colubriformis, Teladorsagia circumcincta, and Haemonchus contortus.Preliminary in vitro studies had reduced L3 T.circumcincta establishment but no effect on L3 T.

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Carbonyl Reduction of Flubendazole in the Human Liver: Strict Stereospecificity, Sex Difference, Low Risk of Drug Interactions

Flubendazole (FLU), an anthelmintic drug of benzimidazole type, is now considered a promising anti-cancer agent due to its tubulin binding ability and low system Versastyler toxicity.The present study was aimed at determining more information about FLU reduction in human liver, because this information has been insufficient until now.Subcellular fr

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